Search hotels in Santa Cruz Region, Bolivia
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Check out these popular cities in Santa Cruz Region
Santa Cruz de la Sierra
1007 hotelsSamaipata
62 hotelsIsla del Mono
2 hotelsEl Pari
39 hotelsSantiago de Chiquitos
3 hotelsHamacas
9 hotelsLa Playa Bejarano
42 hotelsVila El Carmen
5 hotelsBuena Vista
12 hotelsVallegrande
5 hotels
Stay in Santa Cruz Region's best hotels!
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Cosmopolitano Hotel Boutique
Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical centre of Santa Cruz de la Sierra. Guests can enjoy the on-site bar.

TRYP by Wyndham Santa Cruz
Situated in Santa Cruz de la Sierra, 1.6 km from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz features accommodation with an outdoor swimming pool, free private parking, a...

YVY CASA HOTEL
Located in Samaipata, 10 km from Samaipata Fort, YVY CASA HOTEL provides accommodation with a garden, free private parking and a terrace.

El Pueblito Hotel Boutique
Situated in Samaipata, 11 km from Samaipata Fort, El Pueblito Hotel Boutique features accommodation with an outdoor swimming pool, free private parking, a garden and a shared lounge.

Hotel Cortez
Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available.

Hotel By Armonía Santa Cruz
Set in Santa Cruz de la Sierra, 1.6 km from Güembé Biocentre and Guazú Ivaga Park, Hotel By Armonía Santa Cruz offers accommodation with an outdoor swimming pool, free private parking, a garden and a...

La Vida es Bella
Set in Samaipata, 9 km from Samaipata Fort, La Vida es Bella offers accommodation with a garden, free private parking, a shared lounge and a terrace.

Lido Hotel
Lido Hotel features accommodation in Santa Cruz de la Sierra near Metropolitan Cathedral and Gabriel Rene Moreno Autonomous University.

Chairu Eco Hotel
Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra.

Swissotel Santa Cruz de La Sierra
Situated in Santa Cruz de la Sierra, 4.5 km from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra features accommodation with an outdoor swimming pool, free private...

Most booked hotels in Santa Cruz Region in the past month
Popular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Fabulous - What previous guests thought, 269 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.3Good - What previous guests thought, 179 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.9Fabulous - What previous guests thought, 795 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.0Superb - What previous guests thought, 593 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.8Good - What previous guests thought, 1,115 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.1Superb - What previous guests thought, 1,106 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 8.6Fabulous - What previous guests thought, 182 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.2Good - What previous guests thought, 280 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 7.3Good - What previous guests thought, 136 reviewsPopular with guests booking hotels in Santa Cruz Region
Scored out of 10, guest rating 9.0Superb - What previous guests thought, 343 reviews
Santa Cruz Region's best hotels with breakfast
Novotel Santa Cruz De La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.6Fabulous - What previous guests thought, 182 reviewsSet in Santa Cruz de la Sierra, 3.5 km from Gabriel Rene Moreno Autonomous University, Novotel Santa Cruz De La Sierra offers accommodation with an outdoor swimming pool, free private parking, a...
From US$105 per nightChairu Eco Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Fabulous - What previous guests thought, 795 reviewsChairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra.
From US$80 per nightSwissotel Santa Cruz de La Sierra
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.9Fabulous - What previous guests thought, 279 reviewsSituated in Santa Cruz de la Sierra, 4.5 km from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra features accommodation with an outdoor swimming pool, free private parking...
From US$148 per nightDelfines Collection Hotel by Mercure
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very good - What previous guests thought, 296 reviewsLocated in Santa Cruz de la Sierra, 2.2 km from Gabriel Rene Moreno Autonomous University, Delfines Collection Hotel by Mercure provides accommodation with an outdoor swimming pool, free private...
From US$62.57 per nightHampton by Hilton Santa Cruz
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Fabulous - What previous guests thought, 353 reviewsLocated in Santa Cruz de la Sierra, 2.1 km from Gabriel Rene Moreno Autonomous University, Hampton by Hilton Santa Cruz provides accommodation with a fitness centre, free private parking, a garden and...
From US$103.85 per nightMai Suites Apart Hotel
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.7Fabulous - What previous guests thought, 161 reviewsFeaturing 5-star accommodation, Mai Suites Apart Hotel is situated in Santa Cruz de la Sierra, 2 km from Gabriel Rene Moreno Autonomous University and 4.2 km from Arenal Park.
From US$85 per nightLP Equipetrol
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.0Very good - What previous guests thought, 388 reviewsLocated in the commercial district of Equipetrol, this property offers accommodations with free WiFi access in Santa Cruz de la Sierra.
From US$66.89 per nightHotel Sirari By Regina
Hotel in Santa Cruz de la SierraBreakfast optionsScored out of 10, guest rating 8.5Very good - What previous guests thought, 240 reviewsSituated in Santa Cruz de la Sierra, 1.9 km from Gabriel Rene Moreno Autonomous University, Hotel Sirari By Regina features accommodation with an outdoor swimming pool, free private parking, a fitness...
From US$95 per night
Budget hotels in Santa Cruz Region
Prince Hotel
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.0Very good - What previous guests thought, 394 reviewsSet in Santa Cruz de la Sierra, within 1.9 km of Sacred Art Museum and 2.6 km of Metropolitan Cathedral, Prince Hotel offers accommodation with a garden and as well as free private parking for guests...
From US$52 per night- Scored out of 10, guest rating 8.3Very good - What previous guests thought, 314 reviews
The LP Santa Cruz Hotel is a 3-star hotel located few metres from Blacutt Square in central Santa Cruz. It offers rooms with cable TV, a minibar and free Wi-Fi.
From US$61.83 per night - Scored out of 10, guest rating 8.7Fabulous - What previous guests thought, 8 reviews
Set in Santa Cruz de la Sierra, 500 metres from Sacred Art Museum, Santa Cruz Home features a terrace and views of the city.
From US$24 per night - Scored out of 10, guest rating 8.4Very good - What previous guests thought, 14 reviews
Hotel Boutique Plaza24 has a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a shared kitchen and room service.
From US$60 per night Hotel Maywa
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 8.8Fabulous - What previous guests thought, 87 reviewsSituated in Santa Cruz de la Sierra, 3.1 km from Güembé Biocentre and Guazú Ivaga Park, Hotel Maywa features accommodation with a fitness centre, free private parking, a shared lounge and a terrace.
From US$48.45 per night- Scored out of 10, guest rating 7.8Good - What previous guests thought, 1,115 reviews
Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available.
From US$83.62 per night - Scored out of 10, guest rating 6.4Pleasant - What previous guests thought, 259 reviews
Set in Santa Cruz de la Sierra, within 14 km of Arenal Park and 15 km of 24th of September Metropolitan Plaza, Hotel Viru Viru II offers accommodation with a fitness centre and free WiFi throughout...
From US$42.50 per night Hotel Arenal
Hotel in Santa Cruz de la SierraCheap hotelScored out of 10, guest rating 7.3Good - What previous guests thought, 179 reviewsFeaturing a swimming pool, a fitness centre and a restaurant, Hotel Arenal offers rooms with free Wi-Fi and flat-screen TVs in Santa Cruz de la Sierra. Free parking is provided.
From US$69.90 per night
Hotels in Santa Cruz Region that you can book without a credit card
LA CASONA Hotel Boutique
Hotel in CamiriNo credit card neededScored out of 10, guest rating 8.4Very good - What previous guests thought, 17 reviewsBoasting a terrace and barbecue facilities, LA CASONA Hotel Boutique is set in Camiri.
From US$40 per nightEx Hotel Asturias Centrico
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.3Good - What previous guests thought, 136 reviewsSituated in Santa Cruz de la Sierra, 800 metres from Sacred Art Museum, Ex Hotel Asturias Centrico features accommodation with an outdoor swimming pool, free private parking, a garden and a terrace.
From US$26.68 per nightResidencial IKANDIRE ll
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.2Good - What previous guests thought, 280 reviewsResidencial IKANDIRE ll is located in Santa Cruz de la Sierra, 1.4 km from Metropolitan Cathedral and 1.3 km from Güembé Biocentre and Guazú Ivaga Park.
From US$14.50 per nightMansión By Hotel Casablanca
Hotel in SamaipataNo credit card neededScored out of 10, guest rating 6.5Pleasant - What previous guests thought, 6 reviewsMansión By Hotel Casablanca is a 2-star property set in Samaipata. The property is non-smoking and is situated 9.2 km from Samaipata Fort. All rooms in the hotel are fitted with a flat-screen TV.
From US$42.90 per nightHotel Casa Blanca
Hotel in La Playa BejaranoNo credit card neededHotel Casa Blanca is a 5-star property set in La Playa Bejarano. The units come with air conditioning, a flat-screen TV with satellite channels, a fridge, a coffee machine, a shower, free toiletries...
From US$33 per nightHotel el Marqués
Hotel in VallegrandeNo credit card neededScored out of 10, guest rating 7.7Good - What previous guests thought, 14 reviewsFeaturing a terrace, Hotel el Marqués is set in Vallegrande. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the property...
From US$38.50 per nightGaman Hotel Glamping
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.8Good - What previous guests thought, 10 reviewsLocated in Santa Cruz de la Sierra, within 1.2 km of Güembé Biocentre and Guazú Ivaga Park and 1.6 km of 24th of September Metropolitan Plaza, Gaman Hotel Glamping provides accommodation with a garden...
From US$40 per nightGran Hotel Santa Cruz
Hotel in Santa Cruz de la SierraNo credit card neededScored out of 10, guest rating 7.2Good - What previous guests thought, 62 reviewsLocated in Santa Cruz de la Sierra, 200 metres from Sacred Art Museum, Gran Hotel Santa Cruz provides accommodation with an outdoor swimming pool, free private parking, a terrace and a restaurant.
From US$49.50 per night
FAQs about hotels in Santa Cruz Region
See reviews by guests who stayed at hotels in Santa Cruz Region
- From US$153 per nightScored out of 10, guest rating 9.2Superb - What previous guests thought, 219 reviewsRecently fully refurbished, the high standards and professionalism of the staff were only matched by their friendliness and helpfulness. Superb location, restaurants nearby. We stayed 14 nights, a fantastic 5 star experience in the middle of Santa Cruz.Guest review byGrahamUnited Kingdom
- From US$105 per nightScored out of 10, guest rating 9.4Superb - What previous guests thought, 188 reviewsThe hotel has a very special atmosphere. You will always hear the central water feature and the wind in the trees. We found it very relaxing. The breakfast is good and the people very friendly. We would love to have stayed longer.Guest review byJakobGermany
- From US$125.10 per nightScored out of 10, guest rating 8.8Fabulous - What previous guests thought, 488 reviewsThe room was was clean and comfortable. Pool was amazing. Spa and massage were lovely. Reception staff and restaurant staff very friendly. Food was good .Guest review byKatieIreland
- From US$52 per nightScored out of 10, guest rating 8.0Very good - What previous guests thought, 394 reviewsThe hotel more than met all my expectations. The staff was excellent - all of them. They were courteous, kind and very helpful.Guest review byEmilAustralia
- From US$120 per nightScored out of 10, guest rating 7.6Good - What previous guests thought, 541 reviewsI had a late flight and they let me check out later. The swimming pool was so beautiful, I wish I could have swum more there.Guest review byDavidUnited Kingdom
- From US$61.83 per nightScored out of 10, guest rating 8.3Very good - What previous guests thought, 314 reviewsLocation was really close to the city center. Reception was very welcoming. The breakfast had everything needed.Guest review byPedroPortugal
- From US$65 per nightScored out of 10, guest rating 9.0Superb - What previous guests thought, 84 reviewsGreat location. Wonderful service. The best breakfast ever. A perfect place to rest and enjoy Samaipata.Guest review byWalterBolivia
- From US$83.62 per nightScored out of 10, guest rating 7.8Good - What previous guests thought, 1,115 reviewsVery central. Comfortable and great value. Helpful staff. Great shower. Would recommend. Stayed twice.Guest review byMARKUnited Kingdom
- From US$69.90 per nightScored out of 10, guest rating 7.3Good - What previous guests thought, 179 reviewsGood value, comfortable, close to the plaza and helpful staff.Guest review byMichaelPeru
- From US$66.89 per nightScored out of 10, guest rating 8.0Very good - What previous guests thought, 388 reviewsLocation and faculties were fabulous and quite a trendy HotelGuest review bystuartUnited Kingdom
Planning a trip? Get inspired by reviews of cities in Santa Cruz Region
- 6.0
It's a city with not much to offer.
It's a city with not much to offer. You're better off in La Paz, where the views are nicer, the scenery is just better. But you're really much better off in the more rural places, in the mountains, by the lakes and away from the cities.Guest review byOgnyanUnited Kingdom - 8.0
Santa Cruz de la Sierra is an interesting city with a busy...
Santa Cruz de la Sierra is an interesting city with a busy and parcely old part downtown. You find museums, the main plaza with the cathedral, shops for everyone, big restaurants and small places who sell delicious local food. Also thera are some modern shopping malls as also black markets where you find everything you might need for living. Cultural events are offered and some really nice places with abundant semi-tropical vegetation as well as places with a lake to swim and hotels. You can take a taxi or go by bus to almost every place you like, in general it is very safe, only in the outskirts you should be more careful and maybe not go there at nigt. Always take your purse with important things in front of you - just in case! I certainly recommend Santa Cruz for a visit! A little bit outside there are the sanddunes and the botanical garden and other places like the Chiquitania, also very worth visiting!Guest review byCorneliaGermany - 8.0
Friendly people (is famous for its hospitality).
Friendly people (is famous for its hospitality). Is the most productive area of the country, you can find everything you expect of a big city. I like my staying and I will be back with more time and better organized agenda. Given the size of the city and the weather (mostly humid and hot) a car is necessary to visit properly Santa Cruz.Guest review byFlavio David Y.Bolivia